Conditions of employment:
- Eligible to work in U.S. (U.S. citizenship or work permit/authorization)
Why us
- Be part of a team pioneering cutting-edge research at the forefront of precision medicine
- Collaborate with a dynamic and innovative team of scientists in a fast-paced biotech environment
- Competitive benefits package
If you believe you are a strong fit for this position, please apply today!
To Apply: Please send your CV and Cover Letter to claire.roberts@hayatx.com. Please specify the position you are applying for and use the "RES-A " identifier in your cover letter and email subject line.
About the job
We are seeking highly motivated candidates to join our R&D team in San Diego, where you will work at the bench to develop cutting-edge multi-omics technologies aimed at identifying novel long non-coding RNAs (lncRNAs) and exploring their therapeutic potential. The ideal candidate needs a strong background in molecular and RNA biology with experience performing and analyzing a wide array of cell & molecular biology assays in metabolic disease models.
At HAYA, you will be part of a highly collaborative, cross-functional team, leveraging your experience in RNA and molecular biology to design and execute in vitro experiments for the identification of novel targets in metabolic diseases. As an integral early member, you will test pioneering hypotheses, driving novel platform and therapeutic applications.
We are looking for creative, scientifically bold, independent, and goal-oriented scientists. Strong communication skills, a willingness to learn, and the ability to collaborate in a fast-paced entrepreneurial environment are essential.
Primary Responsibilities:
- Optimize new in vitro models and assays for metabolic disease research
- Testing multiple compounds on primary cells to identify novel lncRNA-targeting therapies
- Extract RNA/DNA or proteins from cells and process them for downstream assays
- Generate, interpret, and present data to the R&D teams and senior managers
- Library preparation for different NGS technologies (RNA sequencing, single cell sequencing, etc).
- Maintain an up-to-date electronic notebook record of performed studies.
Qualifications:
The ideal candidate for this position needs:
- M.S. in metabolic diseases, RNA biology, or related field
- Strong background in molecular biology and cell biology
- Experience in metabolic diseases and associated in vitro models and assays
- Experience performing and analyzing a wide array of molecular biology assays including nucleic acid extraction from cells and tissues, qRT-PCR, and ASO transfection
- Experience in library construction for next generation sequencing technologies
- Previous experience with lentiviral production, CRISPR assays, and single cell RNA and ATAC will be a plus
- Publication or patent record will be a plus
HAYA Therapeutics SA is a precision therapeutics company focused on discovering and developing innovative genomic medicines for fibrotic diseases and age-related health conditions, including cancer. Our discovery engine targets long non-coding RNAs (lncRNAs) within the "dark matter" of the human genome to identify novel targets and drug candidates. Our lead therapeutic candidate, HTX-001, is currently progressing through pre-clinical development.
Headquartered at the life sciences park Biopôle in Lausanne, Switzerland with laboratory facilities at JLABS @ San Diego, USA, HAYA is a rapidly growing company led by a world-class team and supported by a strong investor consortium.